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How to strengthen your immune system

I’m seeing an epidemic of autoimmune diseases in my practice – and women are affected in far greater numbers.

They come to me when doctor after doctor has ignored their symptoms or given up on them. You see, the problem is most doctors just don’t understand these diseases.

I’m talking about disorders like lupus… rheumatoid arthritis… fibromyalgia… chronic fatigue syndrome… psoriasis… and multiple sclerosis (MS). But, there are many more.

These are all conditions where your immune system becomes overactive. It attacks your own body instead of diseases and foreign invaders. Right now modern medicine has no cure…

Big Pharma has a long list of drugs to treat symptoms, but it never addresses the real cause.

These drugs try to beat your out-of-control immune system into submission. They also use corticosteroids to try to reduce inflammation.

I don’t prescribe these dangerous drugs. They have terrible side effects like nausea, headaches, and weight gain.

You could also face an increased risk of cancer and life-threatening infections.

Nature has a better solution. Exciting new research shows that a single molecule may reverse autoimmunity. It’s called nicotinamide adenine dinucleotide (NAD+).

NAD+ is found in every living cell and is vital for every process in the human body. It helps transfer energy from the foods you eat to the mitochondria. There it gets converted into cellular energy that affects metabolism, hormone regulation, and immune system function.

It also helps with DNA repair.

Harvard researchers recently found NAD+ can help repair an overactive immune system.1 The team tested NAD+ in mice with an autoimmune condition similar to MS. The condition caused nerve pain, muscle weakness, and sore achy joints.

The mice that received NAD+ had a huge shift in their autoimmune response.

Their immune cells stopped attacking their nerves. Instead, they started protecting the nerves. In other words, NAD+ reset the balance in their immune systems.

But it did even more…

NAD+ repaired and healed nerves damaged by the disease. That’s unheard of in autoimmune conditions.

Other studies show that NAD+ eases and reverses the recurrence of joint and muscle pain. It relieves other chronic conditions that afflict nerve and brain cells.2 It also turns inflammatory immune cells off and on.3

I’ve been recommending NAD+ to my patients for years. Long before it was proven to help autoimmune diseases, NAD+ was known for its anti-aging benefits. It is required to “turn off” genes that accelerate aging processes.

You have plenty of NAD+ when you’re young. But as you age, levels drop. As NAD+ levels decline, mitochondria function is impaired. And you start to see many of the physical signs of aging. Studies link decreases in NAD+ levels to:

  • Brain degeneration
  • Inflammation of blood vessels
  • Fatty liver
  • Increased belly fat
  • Insulin resistance
  • Fatigue and loss of muscle strength

Use the most effective method to get NAD+ benefits

At the Sears Institute for Anti-Aging Medicine, I treat patients with a NAD+ intravenous infusion. Getting NAD+ through IV therapy has a lot of benefits. Because it provides 100% absorption, it’s the most effective way to get it directly into the bloodstream. And that means it’s immediately available for your cells to use.

I often combine the IV with other nutrients your body needs, like vitamin B12, vitamin C, glutathione, magnesium, and zinc.

If you’re interested in IV NAD+ therapy, please call my clinic at 561-784-7852. My staff is happy to answer your questions.

Boost levels easily at home

You can also boost your NAD+ levels with food and supplements. Here’s how…

  1. Eat food rich in niacin. Niacin, also known as vitamin B3, is a precursor for NAD+. Some of the best sources are eggs, green veggies, beans, fish, and whole milk. I highly recommend making sure you eat some of these foods at least once every day.
  2. Supplement. Choose either nicotinic acid or niacinamide. For best results, use 20 mg of nicotinic acid daily, or take 250 mg to 300 mg of niacinamide each day. But, avoid the no-flush forms of niacin. Without the flush, you’re not getting enough to provide any benefit.

To Your Good Health,

Al Sears, MD

 Al Sears, MD, CNS


1. Tullius SG, et al. NAD+ protects against EAE by regulating CD4+ T-cell differentiation. Nature Communications. 2014;5:5101. doi:10.1038/ncomms6101.
2. Martin A, et al. “Role of SIRT1 in autoimmune demyelination and neurodegeneration.” Immunol Res. 2015 Mar;61(3):187-97.
3. Van Gool F, et al. “Intracellular NAD levels regulate tumor necrosis factor protein synthesis in a sirtuin-dependent manner.” Nat Med. 2009 Feb;15(2):206-10.